Ryanair has started flying from Exeter with three new summer routes.
New routes to Malaga and Malta will continue into the winter, running twice weekly from October.
Naples will be served by the no-frills carrier for the summer only.
The arrival of the airline will bring an extra 85,000 passengers to the Devon airport in the first year, Ryanair estimated.
Exeter airport managing director Matt Roach said:“This is the first time we have welcomed Ryanair to Exeter and we’re thrilled to offer customers even more choice from their local airport to these popular sunshine destinations.
“We’re gearing up for a busy 2019 with over 40 routes across the UK and Europe, and we continue to invest in the airport’s facilities to meet growing demand.”
A Ryanair spokeswoman added: “We’re delighted to officially launch our first ever Exeter flights, at our 21st UK airport, with the start of our twice weekly service to Malta, one of three new Exeter summer 2019 routes in addition to Malaga and Naples.
“We’re also pleased to announce our twice weekly services to Malta and Malaga will continue for winter 2019, which will help deliver 85,000 customers through the airport this year.”