Loganair is building a network of Scottish destinations from George Best Belfast City airport following the collapse of Flybe.
Glasgow flights start on September 4 following links to Aberdeen and Inverness which are due to resume from July 6.
The launch of a Dundee service is planned for September 7.
Loganair will become one of the largest airlines at Belfast City, where it flew the first passenger flight when the airport opened in 1983.
All flights will be operated under ‘Safe Steps to Healthy Flying’ protocols announced in by the regional carrier in mid-May. The initiatives mirror those later announced by the European Aviation Safety Agency.
Glasgow will be served wit a double daily frequency on weekdays and Sundays and a single flight on Saturdays using a 49-seat Embraer 145 regional jet.
Loganair has partnerships with major airlines including Emirates, Qatar Airways, Turkish Airlines, United Airlines and Wideroe, enabling travellers from Belfast City to meet onward connecting flights worldwide.
These will enable Belfast City to re-connect to many of the airlines’ networks for the first time since the closure of Flybe in March.
Belfast City commercial director Katy Best said: “Connectivity between Northern Ireland and Scotland is of great importance, and the launch of Loganair’s comprehensive Scottish route network from Belfast City will be welcome news to many frequent flyers.
“Glasgow, Aberdeen and Inverness were popular routes within the Flybe network and we have no doubt there will be significant demand from both business and leisure passengers.
“We are also delighted to see the return of Dundee to our network.”
Loganair chief commercial officer Kay Ryan said: “Our expansion at Belfast City airport is part of a comprehensive plan to re-connect the UK regions as the recovery from the Covid-19 pandemic begins through all walks of life.
“It has been our privilege to continue serving essential routes, and we now very much look forward to re-linking Belfast City with Scotland.
“Loganair flew the first ever passenger flight from Belfast City and we’re delighted to be strengthening these long-standing ties with today’s exciting announcement.”
Glasgow airport managing director Mark Johnston said: “The Glasgow to Belfast City service has always been a popular and convenient route for business travellers given the airport’s close proximity to the Northern Irish capital, so it’s great to see Loganair introduce what will be a twice-daily service from September.
“We are continuing to work with all of our airline partners to support their plans to resume operations to help get the country moving again and to kickstart the economy.
“The introduction of a number of enhanced health measures at the airport has been central to these plans to both protect our staff and passengers and to ensure we help each other to travel safely.”