Singers Michael Ball and David Essex and West End performer Lee Mead will take to the stage during a series of celebrity cruises.
The line said it was launching its "biggest ever line-up of star studded cruises".
The West End Men featuring Lee Mead, winner of the TV programme Any Dream Will Do, will perform on a 12-night Canary Island sailing on Ventura departing on September 29.
Singer, actor and composer David Essex will perform on a Caribbean Transatlantic cruise on Azura setting sail on November 1, while fellow singer Michael Ball will take to the stage on a 10-night Baltic cruise on Aurora from December 9.
Oceana's 12-night western Mediterranean sailing on October 22 will include performances from 80s stars Paul Young, Toyah, Heaven 17, Howard Jones, Carol Decker from T'Pau and Clare Grogan from Altered Images.
Carol Marlow, managing director of P&O Cruises, said: “We’re absolutely thrilled to announce our largest ever choice of star studded cruises.
"Combine these celebrity names with our other famous faces performing at sea; Katherine Jenkins, the Strictly Come Dancing team and our very own celebrity chefs, and I think we have something for everyone, whether you’re a child of the 70s, 80s or 90s.”
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