Flights to Dublin from Leeds Bradford airport are returning from August 1.
Stobart Air, operator of Aer Lingus regional routes, is to run a daily schedule with two flights on Fridays.
Frequency will rise in September wit additional daily flights on Mondays, Tuesdays, Wednesdays and Thursdays.
The service will help with onward connectivity to the US, including pre-clearance at Dublin airport when transatlantic services return.
Passengers will be required to wear mandatory face coverings, with staggered boarding and disembarking taking place in small groups to ensure social distancing can be observed.
Enhanced cleaning protocols have also been introduced to ensure that aircraft are thoroughly prepared between each flight.
Leeds Bradford airport chief commercial officer Joanna Wild said: “The connection between Leeds and Dublin is an important one for leisure and businesses across the Yorkshire region.
“We’re delighted to see this route return safely and look forward to welcoming passengers back over the summer.”
Stobart Air managing director Andy Jolly added: “Passengers can be assured that enhanced health and safety measures in accordance with European Aviation Safety Agency (EASA), and the European Centre for Disease Prevention and Control (ECDC) guidance are now in place to protect our passengers, our staff, and our airline partners.”