The Thomas Cook Group has placed 77 Dublin-based staff under consultation over possible redundancies.
As many as 46 staff in two Thomas Cook shops will undergo the 30-day consultation, which starts next week, along with 15 staff at the Direct Holidays shop in the city.
The remaining 16 staff all work for Thomas Cook operator brands Direct Holidays, Sunworld and Panorama.
A Thomas Cook spokesman said: "This announcement is in no way a reflection on the dedication and loyalty of colleagues in Dublin.
"Should the proposals be approved during the 30-day consultation period, our priority is to retain as many people as possible and to offer our full support to those who may be affected.
"Over the past few years, Thomas Cook and the Irish travel market have changed dramatically, as have our customers' buying habits and booking trends.
"In light of this, we have reviewed our operations and the services we provide to ensure we continue to meet the changing needs of the business and our customers."
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